MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generation sequencing data

The growing number of next-generation sequencing (NGS) data presents a unique opportunity to study the combined impact of mitochondrial and nuclear-encoded genetic variation in complex disease. Mitochondrial DNA variants and in particular, heteroplasmic variants, are critical for determining human d...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Larry N., Ennis, Brian, Loneragan, Bryn, Tsao, Noah L., Lopez Sanchez, M. Isabel G., Li, Jianping, Acheampong, Patrick, Tran, Oanh, Trounce, Ian A., Zhu, Yuankun, Potluri, Prasanth, Emanuel, Beverly S., Rader, Daniel J., Arany, Zoltan, Damrauer, Scott M., Resnick, Adam C., Anderson, Stewart A., Wallace, Douglas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610268/
https://www.ncbi.nlm.nih.gov/pubmed/34762648
http://dx.doi.org/10.1371/journal.pcbi.1009594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610268/
https://www.ncbi.nlm.nih.gov/pubmed/34762648
http://dx.doi.org/10.1371/journal.pcbi.1009594

Ejemplares similares