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Mad1’s ability to interact with Mad2 is essential to regulate and monitor meiotic synapsis in C. elegans

Meiotic homolog synapsis is essential to ensure accurate segregation of chromosomes during meiosis. In C. elegans, proper regulation of synapsis and a checkpoint that monitors synapsis relies on the spindle checkpoint components, Mad1 and Mad2, and Pairing Centers (PCs), cis-acting loci that interac...

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Detalles Bibliográficos
Autores principales: Devigne, Alice, Bhalla, Needhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610272/
https://www.ncbi.nlm.nih.gov/pubmed/34762652
http://dx.doi.org/10.1371/journal.pgen.1009598