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Phylogenetic analysis of the bacterial Pro-Pro-endopeptidase domain reveals a diverse family including secreted and membrane anchored proteins

Pro-Pro-endopeptidases (PPEP, EC 3.4.24.89) are secreted, zinc metalloproteases that have the unusual capacity to cleave a peptide bond between two prolines, a bond that is generally less sensitive to proteolytic cleavage. Two well studied members of the family are PPEP-1 and PPEP-2, produced by Clo...

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Detalles Bibliográficos
Autores principales: van Leeuwen, Hans C, Roelofs, Dick, Corver, Jeroen, Hensbergen, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610288/
https://www.ncbi.nlm.nih.gov/pubmed/34841315
http://dx.doi.org/10.1016/j.crmicr.2021.100024