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The core Cas1 protein of CRISPR-Cas I-B in Leptospira shows metal-tunable nuclease activity
Leptospira interrogans serovar Copenhageni strain Fiocruz L1-130 is the causative agent of leptospirosis in animals and humans. This organism carries a functional cas1 gene classified under CRISPR-Cas I-B. In this study, using various nuclease assays and bioinformatics analysis, we report that the r...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610301/ https://www.ncbi.nlm.nih.gov/pubmed/34841349 http://dx.doi.org/10.1016/j.crmicr.2021.100059 |