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The CRISPR-associated Cas4 protein from Leptospira interrogans demonstrate versatile nuclease activity

The Cas4 protein is one of the core CRISPR-associated (Cas) proteins implicated in the adaptation module in many variants of the CRISPR-Cas system in prokaryotes against the invading genetic elements. Cas4 is recognized as a DNA exonuclease that contains a RecB nuclease domain and a Fe-S cluster-bin...

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Detalles Bibliográficos
Autores principales: Dixit, Bhuvan, Anand, Vineet, Hussain, Md. Saddam, Kumar, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610317/
https://www.ncbi.nlm.nih.gov/pubmed/34841331
http://dx.doi.org/10.1016/j.crmicr.2021.100040