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The CRISPR-associated Cas4 protein from Leptospira interrogans demonstrate versatile nuclease activity
The Cas4 protein is one of the core CRISPR-associated (Cas) proteins implicated in the adaptation module in many variants of the CRISPR-Cas system in prokaryotes against the invading genetic elements. Cas4 is recognized as a DNA exonuclease that contains a RecB nuclease domain and a Fe-S cluster-bin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610317/ https://www.ncbi.nlm.nih.gov/pubmed/34841331 http://dx.doi.org/10.1016/j.crmicr.2021.100040 |