BRAF(V600E) induces reversible mitotic arrest in human melanocytes via microRNA-mediated suppression of AURKB

Benign melanocytic nevi frequently emerge when an acquired BRAF(V600E) mutation triggers unchecked proliferation and subsequent arrest in melanocytes. Recent observations have challenged the role of oncogene-induced senescence in melanocytic nevus formation, necessitating investigations into alterna...

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Detalles Bibliográficos
Autores principales: McNeal, Andrew S, Belote, Rachel L, Zeng, Hanlin, Urquijo, Marcus, Barker, Kendra, Torres, Rodrigo, Curtin, Meghan, Shain, A Hunter, Andtbacka, Robert HI, Holmen, Sheri, Lum, David H, McCalmont, Timothy H, VanBrocklin, Matt W, Grossman, Douglas, Wei, Maria L, Lang, Ursula E, Judson-Torres, Robert L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610417/
https://www.ncbi.nlm.nih.gov/pubmed/34812139
http://dx.doi.org/10.7554/eLife.70385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610417/
https://www.ncbi.nlm.nih.gov/pubmed/34812139
http://dx.doi.org/10.7554/eLife.70385

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