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The Amyloid Precursor Protein C99 Fragment Modulates Voltage-Gated Potassium Channels

BACKGROUND/AIMS: The Amyloid Precursor Protein (APP) is involved in the regulation of multiple cellular functions via protein-protein interactions and has been most studied with respect to Alzheimer’s disease (AD). Abnormal processing of the single transmembrane-spanning C99 fragment of APP contribu...

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Detalles Bibliográficos
Autores principales: Manville, Rían W., Abbott, Geoffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610427/
https://www.ncbi.nlm.nih.gov/pubmed/34318654
http://dx.doi.org/10.33594/000000397