Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis

Mechanistic studies of Drosophila lymph gland hematopoiesis are limited by the availability of cell-type-specific markers. Using a combination of bulk RNA-Seq of FACS-sorted cells, single-cell RNA-Seq, and genetic dissection, we identify new blood cell subpopulations along a developmental trajectory...

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Detalles Bibliográficos
Autores principales: Girard, Juliet R, Goins, Lauren M, Vuu, Dung M, Sharpley, Mark S, Spratford, Carrie M, Mantri, Shreya R, Banerjee, Utpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610493/
https://www.ncbi.nlm.nih.gov/pubmed/34713801
http://dx.doi.org/10.7554/eLife.67516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610493/
https://www.ncbi.nlm.nih.gov/pubmed/34713801
http://dx.doi.org/10.7554/eLife.67516

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