Convergent HIV-1 Evolution upon Targeted Destabilization of the gp120-gp41 Interface

The HIV-1 envelope glycoprotein (Env) trimer is responsible for viral entry into target cells and is the sole target of neutralizing antibodies. The Env protein is therefore the focus of HIV-1 vaccine design. Env consists of two noncovalently linked subunits (gp120 and gp41) that form a trimer of he...

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Detalles Bibliográficos
Autores principales: Torrents de la Peña, Alba, del Moral Sánchez, Iván, Burger, Judith A., Bontjer, Ilja, Isik, Gözde, Eggink, Dirk, van Gils, Marit J., Sanders, Rogier W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610599/
https://www.ncbi.nlm.nih.gov/pubmed/34586861
http://dx.doi.org/10.1128/JVI.00532-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610599/
https://www.ncbi.nlm.nih.gov/pubmed/34586861
http://dx.doi.org/10.1128/JVI.00532-21

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