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CSF Synaptic Biomarkers in the Preclinical Stage of Alzheimer Disease and Their Association With MRI and PET: A Cross-sectional Study
BACKGROUND AND OBJECTIVES: To determine whether CSF synaptic biomarkers are altered in the early preclinical stage of the Alzheimer continuum and associated with Alzheimer disease (AD) risk factors, primary pathology, and neurodegeneration markers. METHODS: This cross-sectional study was performed i...
Autores principales: | Milà-Alomà, Marta, Brinkmalm, Ann, Ashton, Nicholas J., Kvartsberg, Hlin, Shekari, Mahnaz, Operto, Grégory, Salvadó, Gemma, Falcon, Carles, Gispert, Juan Domingo, Vilor-Tejedor, Natalia, Arenaza-Urquijo, Eider M., Grau-Rivera, Oriol, Sala-Vila, Aleix, Sanchez-Benavides, Gonzalo, González-de-Echávarri, José María, Minguillon, Carolina, Fauria, Karine, Niñerola-Baizán, Aida, Perissinotti, Andrés, Kollmorgen, Gwendlyn, Suridjan, Ivonne, Zetterberg, Henrik, Molinuevo, José Luis, Blennow, Kaj, Suárez-Calvet, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610620/ https://www.ncbi.nlm.nih.gov/pubmed/34556565 http://dx.doi.org/10.1212/WNL.0000000000012853 |
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