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A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge

An ideal vaccine against SARS-CoV-2 is expected to elicit broad immunity to prevent viral infection and disease, with efficient viral clearance in the upper respiratory tract (URT). Here, the N protein and prefusion-full S protein (SFL(mut)) are combined with flagellin (KF) and cyclic GMP-AMP (cGAMP...

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Detalles Bibliográficos
Autores principales: Jiang, Wenwen, Shi, Li, Cai, Lukui, Wang, Xiaoyu, Li, Jingyan, Li, Heng, Liang, Jiangli, Gu, Qin, Ji, Guang, Li, Jing, Liu, Longding, Sun, Mingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610932/
https://www.ncbi.nlm.nih.gov/pubmed/34863353
http://dx.doi.org/10.1016/j.celrep.2021.110112