Cargando…
A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge
An ideal vaccine against SARS-CoV-2 is expected to elicit broad immunity to prevent viral infection and disease, with efficient viral clearance in the upper respiratory tract (URT). Here, the N protein and prefusion-full S protein (SFL(mut)) are combined with flagellin (KF) and cyclic GMP-AMP (cGAMP...
Autores principales: | Jiang, Wenwen, Shi, Li, Cai, Lukui, Wang, Xiaoyu, Li, Jingyan, Li, Heng, Liang, Jiangli, Gu, Qin, Ji, Guang, Li, Jing, Liu, Longding, Sun, Mingbo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610932/ https://www.ncbi.nlm.nih.gov/pubmed/34863353 http://dx.doi.org/10.1016/j.celrep.2021.110112 |
Ejemplares similares
-
Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model
por: Jiang, Wenwen, et al.
Publicado: (2022) -
Dose-Sparing Intradermal DTaP-sIPV Immunization With a Hollow Microneedle Leads to Superior Immune Responses
por: Zuo, Weilun, et al.
Publicado: (2021) -
Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines
por: Hussein, Waleed M., et al.
Publicado: (2016) -
Immunogenicity of a Candidate DTacP-sIPV Combined Vaccine and Its Protection Efficacy against Pertussis in a Rhesus Macaque Model
por: Wang, Xiaoyu, et al.
Publicado: (2021) -
Porphyromonas gingivalis induces an inflammatory response via the cGAS-STING signaling pathway in a periodontitis mouse model
por: Bi, Rong, et al.
Publicado: (2023)