A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation

Apical-basal cell polarity and lumen formation are essential features of many epithelial tissues, which are disrupted in diseases like cancer. Here, we describe a proteomics-based screen to identify proteins involved in lumen formation in three-dimensional spheroid cultures. We established a suspens...

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Detalles Bibliográficos
Autores principales: Wang, Li-Ting, Proulx, Marie-Ève, Kim, Anne D., Lelarge, Virginie, McCaffrey, Luke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610992/
https://www.ncbi.nlm.nih.gov/pubmed/34815476
http://dx.doi.org/10.1038/s41598-021-02178-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610992/
https://www.ncbi.nlm.nih.gov/pubmed/34815476
http://dx.doi.org/10.1038/s41598-021-02178-2

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