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A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation
Apical-basal cell polarity and lumen formation are essential features of many epithelial tissues, which are disrupted in diseases like cancer. Here, we describe a proteomics-based screen to identify proteins involved in lumen formation in three-dimensional spheroid cultures. We established a suspens...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610992/ https://www.ncbi.nlm.nih.gov/pubmed/34815476 http://dx.doi.org/10.1038/s41598-021-02178-2 |