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Single-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastoma

Retinoblastoma is a childhood retinal tumour that is the most common primary malignant intraocular tumour. However, it has been challenging to identify the cell types associated with genetic complexity. Here, we performed single-cell RNA sequencing on 14,739 cells from two retinoblastoma samples to...

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Detalles Bibliográficos
Autores principales: Yang, Jie, Li, Yongyun, Han, Yanping, Feng, Yiyi, Zhou, Min, Zong, Chunyan, He, Xiaoyu, Jia, Renbing, Xu, Xiaofang, Fan, Jiayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611004/
https://www.ncbi.nlm.nih.gov/pubmed/34815392
http://dx.doi.org/10.1038/s41419-021-04390-4