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Single-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastoma
Retinoblastoma is a childhood retinal tumour that is the most common primary malignant intraocular tumour. However, it has been challenging to identify the cell types associated with genetic complexity. Here, we performed single-cell RNA sequencing on 14,739 cells from two retinoblastoma samples to...
Autores principales: | Yang, Jie, Li, Yongyun, Han, Yanping, Feng, Yiyi, Zhou, Min, Zong, Chunyan, He, Xiaoyu, Jia, Renbing, Xu, Xiaofang, Fan, Jiayan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611004/ https://www.ncbi.nlm.nih.gov/pubmed/34815392 http://dx.doi.org/10.1038/s41419-021-04390-4 |
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