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Mapping enzyme catalysis with metabolic biosensing

Enzymes are represented across a vast space of protein sequences and structural forms and have activities that far exceed the best chemical catalysts; however, engineering them to have novel or enhanced activity is limited by technologies for sensing product formation. Here, we describe a general an...

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Detalles Bibliográficos
Autores principales: Xu, Linfeng, Chang, Kai-Chun, Payne, Emory M., Modavi, Cyrus, Liu, Leqian, Palmer, Claire M., Tao, Nannan, Alper, Hal S., Kennedy, Robert T., Cornett, Dale S., Abate, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611028/
https://www.ncbi.nlm.nih.gov/pubmed/34815408
http://dx.doi.org/10.1038/s41467-021-27185-9