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EZH2 presents a therapeutic target for neuroendocrine tumors of the small intestine

Small intestinal neuroendocrine tumors (SI-NETs) are slow-growing tumors that seem genetically quite stable without highly recurrent mutations, but are epigenetically dysregulated. In contrast to the undetectable expression of the enhancer of zeste homolog 2 (EZH2) histone methyltransferase in the e...

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Detalles Bibliográficos
Autores principales: Barazeghi, Elham, Hellman, Per, Norlén, Olov, Westin, Gunnar, Stålberg, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611048/
https://www.ncbi.nlm.nih.gov/pubmed/34815475
http://dx.doi.org/10.1038/s41598-021-02181-7