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G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators

G-protein-coupled receptors (GPCRs), especially chemokine receptors, play a central role in the regulation of T cell migration. Various GPCRs are upregulated in activated CD4 T cells, including P2Y10, a putative lysophospholipid receptor that is officially still considered an orphan GPCR, i.e., a re...

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Detalles Bibliográficos
Autores principales: Gurusamy, Malarvizhi, Tischner, Denise, Shao, Jingchen, Klatt, Stephan, Zukunft, Sven, Bonnavion, Remy, Günther, Stefan, Siebenbrodt, Kai, Kestner, Roxane-Isabelle, Kuhlmann, Tanja, Fleming, Ingrid, Offermanns, Stefan, Wettschureck, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611058/
https://www.ncbi.nlm.nih.gov/pubmed/34815397
http://dx.doi.org/10.1038/s41467-021-26882-9