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Discrete regulatory modules instruct hematopoietic lineage commitment and differentiation

Lineage commitment and differentiation is driven by the concerted action of master transcriptional regulators at their target chromatin sites. Multiple efforts have characterized the key transcription factors (TFs) that determine the various hematopoietic lineages. However, the temporal interactions...

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Detalles Bibliográficos
Autores principales: Georgolopoulos, Grigorios, Psatha, Nikoletta, Iwata, Mineo, Nishida, Andrew, Som, Tannishtha, Yiangou, Minas, Stamatoyannopoulos, John A., Vierstra, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611072/
https://www.ncbi.nlm.nih.gov/pubmed/34815405
http://dx.doi.org/10.1038/s41467-021-27159-x