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Discrete regulatory modules instruct hematopoietic lineage commitment and differentiation
Lineage commitment and differentiation is driven by the concerted action of master transcriptional regulators at their target chromatin sites. Multiple efforts have characterized the key transcription factors (TFs) that determine the various hematopoietic lineages. However, the temporal interactions...
Autores principales: | Georgolopoulos, Grigorios, Psatha, Nikoletta, Iwata, Mineo, Nishida, Andrew, Som, Tannishtha, Yiangou, Minas, Stamatoyannopoulos, John A., Vierstra, Jeff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611072/ https://www.ncbi.nlm.nih.gov/pubmed/34815405 http://dx.doi.org/10.1038/s41467-021-27159-x |
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