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Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood

Venous air embolism, which may complicate medical and surgical procedures, activates complement and triggers thromboinflammation. In lepirudin-anticoagulated human whole blood, we examined the effect of air bubbles on complement and its role in thromboinflammation. Whole blood from 16 donors was inc...

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Detalles Bibliográficos
Autores principales: Storm, Benjamin S., Christiansen, Dorte, Fure, Hilde, Ludviksen, Judith K., Lau, Corinna, Lambris, John D., Woodruff, Trent M., Brekke, Ole-Lars, Braaten, Tonje, Nielsen, Erik W., Mollnes, Tom Eirik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611197/
https://www.ncbi.nlm.nih.gov/pubmed/34732467
http://dx.doi.org/10.4049/jimmunol.2100308