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Synthesis of Pore-Size-Tunable Mesoporous Silica Nanoparticles by Simultaneous Sol-Gel and Radical Polymerization to Enhance Silibinin Dissolution

BACKGROUND: Silibinin (SBN), a major active constituent of milk thistle seeds, exhibits numerous pharmacological activities. However, its oral bioavailability is low due to poor water solubility. This study aimed to develop a new synthetic approach for tuning the pore characteristics of mesoporous s...

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Detalles Bibliográficos
Autores principales: Shafiee, Mina, Abolmaali, Samirasadat, Abedanzadeh, Mozhgan, Abedi, Mehdi, Tamaddon, Alimohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611219/
https://www.ncbi.nlm.nih.gov/pubmed/34840388
http://dx.doi.org/10.30476/ijms.2020.86173.1595