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Peptides Targeting Fms-Related Tyrosine Kinase-4 Activate the Function of Natural Killer Cells in Acute Myeloid Leukemia

BACKGROUND AND OBJECTIVES: The increased expression for the Fms-related tyrosine kinase-4 (FLT-4, known as VEGFR-3) is relevant to dysfunctional natural killer (NK) cells in acute myeloid leukemia (AML). MAZ51 (M), a VEGFR-3 inhibiting chemical, was effectively restored the function of NK cells via...

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Detalles Bibliográficos
Autores principales: Park, Soojin, Kim, Hee-Je, Hwang, Hee-Sun, Han, A-Reum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611315/
https://www.ncbi.nlm.nih.gov/pubmed/34158419
http://dx.doi.org/10.15283/ijsc21083