A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis

The integral membrane protein Apq12 is an important nuclear envelope (NE)/endoplasmic reticulum (ER) modulator that cooperates with the nuclear pore complex (NPC) biogenesis factors Brl1 and Brr6. How Apq12 executes these functions is unknown. Here, we identified a short amphipathic α-helix (AαH) in...

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Detalles Bibliográficos
Autores principales: Zhang, Wanlu, Khan, Azqa, Vitale, Jlenia, Neuner, Annett, Rink, Kerstin, Lüchtenborg, Christian, Brügger, Britta, Söllner, Thomas H., Schiebel, Elmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611336/
https://www.ncbi.nlm.nih.gov/pubmed/34814743
http://dx.doi.org/10.1098/rsob.210250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611336/
https://www.ncbi.nlm.nih.gov/pubmed/34814743
http://dx.doi.org/10.1098/rsob.210250

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