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Hypoglycaemia combined with mild hypokalaemia reduces the heart rate and causes abnormal pacemaker activity in a computational model of a human sinoatrial cell

Low blood glucose, hypoglycaemia, has been implicated as a possible contributing factor to sudden cardiac death (SCD) in people with diabetes but it is challenging to investigate in clinical studies. We hypothesized the effects of hypoglycaemia on the sinoatrial node (SAN) in the heart to be a candi...

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Detalles Bibliográficos
Autores principales: Bernjak, Alan, Iqbal, Ahmed, Heller, Simon R., Clayton, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611338/
https://www.ncbi.nlm.nih.gov/pubmed/34814734
http://dx.doi.org/10.1098/rsif.2021.0612