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Expression of neurofibromin 1 in colorectal cancer and cetuximab resistance

Neurofibromin 1 (NF1) is a tumor suppressor that has been previously reported to regulate RAS-MAPK signaling. The present study investigated the possible relationship between NF1 expression and anti-EGFR antibody (cetuximab) sensitivity in colorectal cancer cell lines. In addition, primary or metast...

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Detalles Bibliográficos
Autores principales: Tak, Eunyoung, Kim, Minhee, Cho, Youngra, Choi, Sueun, Kim, Jihun, Han, Buhm, Kim, Hyung-Don, Jang, Chloe Soo-Hyun, Kim, Jeong Eun, Hong, Yong Sang, Kim, Sun Young, Kim, Tae Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611403/
https://www.ncbi.nlm.nih.gov/pubmed/34779495
http://dx.doi.org/10.3892/or.2021.8226