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An analog-sensitive allele of Aurora kinase B is lethal in mouse

The mammalian genome encodes three Aurora protein kinase homologs (AURKA/B/C) which regulate chromosome segregation in nearly every cell type. AURKC expression is largely limited to meiotic cells. Because of the similarity in sequences between AURKB and AURKC, determining their separate functions du...

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Detalles Bibliográficos
Autores principales: Vazquez, Berta N., Quartuccio, Suzanne M., Schindler, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611416/
https://www.ncbi.nlm.nih.gov/pubmed/34841221
http://dx.doi.org/10.17912/micropub.biology.000491