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HO-1/BMMSC perfusion using a normothermic machine perfusion system reduces the acute rejection of DCD liver transplantation by regulating NKT cell co-inhibitory receptors in rats

BACKGROUND: Liver transplantation (LT) is required in many end-stage liver diseases. Donation after cardiac death (DCD) livers are often used, and treatment of acute rejection (ACR) requires the use of immunosuppressive drugs that are associated with complications. Bone marrow mesenchymal stem cells...

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Detalles Bibliográficos
Autores principales: Cao, Huan, Wu, Longlong, Tian, Xuan, Zheng, Weiping, Yuan, Mengshu, Li, Xiang, Tian, Xiaorong, Wang, Yuxin, Song, Hongli, Shen, Zhongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611848/
https://www.ncbi.nlm.nih.gov/pubmed/34819139
http://dx.doi.org/10.1186/s13287-021-02647-5