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Hydroxychloroquine and azithromycin used alone or combined are not effective against SARS-CoV-2 ex vivo and in a hamster model

Drug repositioning has been used extensively since the beginning of the COVID-19 pandemic in an attempt to identify antiviral molecules for use in human therapeutics. Hydroxychloroquine and azithromycin have shown inhibitory activity against SARS-CoV-2 replication in different cell lines. Based on s...

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Detalles Bibliográficos
Autores principales: Cochin, Maxime, Touret, Franck, Driouich, Jean-Sélim, Moureau, Gregory, Petit, Paul-Rémi, Laprie, Caroline, Solas, Caroline, de Lamballerie, Xavier, Nougairède, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611861/
https://www.ncbi.nlm.nih.gov/pubmed/34838583
http://dx.doi.org/10.1016/j.antiviral.2021.105212