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Mutational signature analysis in non-small cell lung cancer patients with a high tumor mutational burden

BACKGROUND: Lung cancer is the leading cause of cancer death worldwide. With the growing number of targeted therapies and the introduction of immuno-oncology (IO), personalized medicine has become standard of care in patients with metastatic disease. The development of predictive and prognostic biom...

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Detalles Bibliográficos
Autores principales: van den Heuvel, Guus R. M., Kroeze, Leonie I., Ligtenberg, Marjolijn J. L., Grünberg, Katrien, Jansen, Erik A. M., von Rhein, Daniel, de Voer, Richarda M., van den Heuvel, Michel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611965/
https://www.ncbi.nlm.nih.gov/pubmed/34819052
http://dx.doi.org/10.1186/s12931-021-01871-0