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Oleate Hydratase (OhyA) Is a Virulence Determinant in Staphylococcus aureus

Staphylococcus aureus is an important pathogen that relies on a variety of mechanisms to evade and counteract the immune system. We show that S. aureus uses oleate hydratase (OhyA) to convert host cis-9 unsaturated fatty acids to their 10-hydroxy derivatives in human serum and at the infection site...

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Detalles Bibliográficos
Autores principales: Radka, Christopher D., Batte, Justin L., Frank, Matthew W., Rosch, Jason W., Rock, Charles O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612147/
https://www.ncbi.nlm.nih.gov/pubmed/34817231
http://dx.doi.org/10.1128/Spectrum.01546-21