Brain Somatic Mutation in Aging and Alzheimer’s Disease

Somatic mutations arise postzygotically, producing genetic differences between cells in an organism. Well established as a driver of cancer, somatic mutations also exist in nonneoplastic cells, including in the brain. Technological advances in nucleic acid sequencing have enabled recent break-throug...

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Detalles Bibliográficos
Autores principales: Miller, Michael B., Reed, Hannah C., Walsh, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612367/
https://www.ncbi.nlm.nih.gov/pubmed/33979534
http://dx.doi.org/10.1146/annurev-genom-121520-081242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612367/
https://www.ncbi.nlm.nih.gov/pubmed/33979534
http://dx.doi.org/10.1146/annurev-genom-121520-081242

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