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Brain Somatic Mutation in Aging and Alzheimer’s Disease
Somatic mutations arise postzygotically, producing genetic differences between cells in an organism. Well established as a driver of cancer, somatic mutations also exist in nonneoplastic cells, including in the brain. Technological advances in nucleic acid sequencing have enabled recent break-throug...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612367/ https://www.ncbi.nlm.nih.gov/pubmed/33979534 http://dx.doi.org/10.1146/annurev-genom-121520-081242 |