A Unique Type of Highly-Activated Microglia Evoking Brain Inflammation via Mif/Cd74 Signaling Axis in Aged Mice

Senescence-associated alterations of microglia have only recently been appreciated in the aged brain. Although our previous study has reported chronic inflammation in aged microglia, the mechanism remains poorly understood. Here, we performed morphological detection and transcriptomic analysis of ag...

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Detalles Bibliográficos
Autores principales: Jin, Chenghao, Shao, Yijie, Zhang, Xiaotao, Xiang, Jiani, Zhang, Ruize, Sun, Zeyu, Mei, Shuhao, Zhou, Jingyi, Zhang, Jianmin, Shi, Ligen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612608/
https://www.ncbi.nlm.nih.gov/pubmed/34881090
http://dx.doi.org/10.14336/AD.2021.0520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612608/
https://www.ncbi.nlm.nih.gov/pubmed/34881090
http://dx.doi.org/10.14336/AD.2021.0520

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