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Tip110 Expression Facilitates the Release of HEXIM1 and pTEFb from the 7SK Ribonucleoprotein Complex Involving Regulation of the Intracellular Redox Level

HIV-1 Tat-interacting protein of 110 kDa (Tip110; p110(nrb)/SART3) has been identified to be important for HIV gene transcription and several host gene expression. In this study, we showed that Tip110 was present in the 7SK snRNP through direct binding to MEPCE, a component of the 7SK snRNP complex....

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Detalles Bibliográficos
Autores principales: Liu, Ying, Li, Lu, Timani, Khalid, White, Carl, He, Johnny J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612609/
https://www.ncbi.nlm.nih.gov/pubmed/34881089
http://dx.doi.org/10.14336/AD.2021.0528