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Cytokine-scavenging nanodecoys reconstruct osteoclast/osteoblast balance toward the treatment of postmenopausal osteoporosis

Imbalance between osteoblasts and osteoclasts accounts for the incidence and deterioration of postmenopausal osteoporosis. Abnormally elevated RANKL and TNF-α levels after menopause promote osteoclast formation and inhibit osteoblast differentiation, respectively. Here, nanodecoys capable of scaveng...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Deng, Yekun, Liu, Zhongmin, Yin, Mengyuan, Hou, Mengying, Zhao, Ziyin, Zhou, Xiaozhong, Yin, Lichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612675/
https://www.ncbi.nlm.nih.gov/pubmed/34818042
http://dx.doi.org/10.1126/sciadv.abl6432