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Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting

While mouse remains the most popular model, the conservation of parental-to-embryonic epigenetic transition across mammals is poorly defined. Through analysis of oocytes and early embryos in human, bovine, porcine, rat, and mouse, we revealed remarkable species-specific innovations as no single anim...

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Detalles Bibliográficos
Autores principales: Lu, Xukun, Zhang, Yu, Wang, Lijuan, Wang, Leyun, Wang, Huili, Xu, Qianhua, Xiang, Yunlong, Chen, Chaolei, Kong, Feng, Xia, Weikun, Lin, Zili, Ma, Sinan, Liu, Ling, Wang, Xiangguo, Ni, Hemin, Li, Wei, Guo, Yong, Xie, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612685/
https://www.ncbi.nlm.nih.gov/pubmed/34818044
http://dx.doi.org/10.1126/sciadv.abi6178