Senolytic Therapy to Modulate the Progression of Alzheimer’s Disease (SToMP-AD): A Pilot Clinical Trial

Preclinical studies indicate an age-associated accumulation of senescent cells across multiple organ systems. Emerging evidence suggests that tau protein accumulation, which closely correlates with cognitive decline in Alzheimer’s disease and other tauopathies, drives cellular senescence in the brai...

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Detalles Bibliográficos
Autores principales: Gonzales, Mitzi M., Garbarino, V. R., Marques Zilli, E., Petersen, R. C., Kirkland, J. L., Tchkonia, T., Musi, N., Seshadri, S., Craft, S., Orr, Miranda E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Special Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612719/
https://www.ncbi.nlm.nih.gov/pubmed/35098970
http://dx.doi.org/10.14283/jpad.2021.62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612719/
https://www.ncbi.nlm.nih.gov/pubmed/35098970
http://dx.doi.org/10.14283/jpad.2021.62

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