Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage

BACKGROUND AND PURPOSE: Mitochondria play a central role in the host response to viral infection and immunity, being key to antiviral signaling and exacerbating inflammatory processes. Mitochondria and Toll-like receptor (TLR) have been suggested as potential targets in SARS-CoV-2 infection. However...

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Detalles Bibliográficos
Autores principales: Costa, Tiago J., Potje, Simone R., Fraga-Silva, Thais F.C., da Silva-Neto, Júlio A., Barros, Paula R., Rodrigues, Daniel, Machado, Mirele R., Martins, Ronaldo B., Santos-Eichler, Rosangela A., Benatti, Maira N., de Sá, Keyla S.G., Almado, Carlos Eduardo L., Castro, Ítalo A., Pontelli, Marjorie C., Serra, Leonardo La, Carneiro, Fernando S., Becari, Christiane, Louzada-Junior, Paulo, Oliveira, Rene D.R., Zamboni, Dario S., Arruda, Eurico, Auxiliadora-Martins, Maria, Giachini, Fernanda R.C., Bonato, Vânia L.D., Zachara, Natasha E., Bomfim, Gisele F., Tostes, Rita C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612754/
https://www.ncbi.nlm.nih.gov/pubmed/34838735
http://dx.doi.org/10.1016/j.vph.2021.106946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612754/
https://www.ncbi.nlm.nih.gov/pubmed/34838735
http://dx.doi.org/10.1016/j.vph.2021.106946

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