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Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease

Transposition has a key role in reshaping genomes of all living organisms(1). Insertion sequences of IS200/IS605 and IS607 families(2) are among the simplest mobile genetic elements and contain only the genes that are required for their transposition and its regulation. These elements encode tnpA tr...

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Detalles Bibliográficos
Autores principales: Karvelis, Tautvydas, Druteika, Gytis, Bigelyte, Greta, Budre, Karolina, Zedaveinyte, Rimante, Silanskas, Arunas, Kazlauskas, Darius, Venclovas, Česlovas, Siksnys, Virginijus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612924/
https://www.ncbi.nlm.nih.gov/pubmed/34619744
http://dx.doi.org/10.1038/s41586-021-04058-1