IL-2/IL-2R Antibody Complex Enhances Treg-Induced Neuroprotection by Dampening TNF-α Inflammation in an In Vitro Stroke Model

The present in vitro study showed that IL-2/IL-2R antibody complex facilitates Treg-induced neuroprotection in the oxygen glucose deprivation/reoxygenation (OGD/R) model of stroke. First, we examined the role of IL-2/IL-2R-treated Tregs in OGD/R-exposed rat primary cortical cells (PCCs), which repre...

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Detalles Bibliográficos
Autores principales: Borlongan, Mia C., Kingsbury, Chase, Salazar, Felipe Esparza, Toledo, Alma R. Lezama, Monroy, German Rivera, Sadanandan, Nadia, Cozene, Blaise, Gonzales-Portillo, Bella, Saft, Madeline, Wang, Zhen-Jie, Moscatello, Alexa, Lee, Jea Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613084/
https://www.ncbi.nlm.nih.gov/pubmed/33830475
http://dx.doi.org/10.1007/s12017-021-08656-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613084/
https://www.ncbi.nlm.nih.gov/pubmed/33830475
http://dx.doi.org/10.1007/s12017-021-08656-0

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