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Impact of Inflammation on Cytochromes P450 Activity in Pediatrics: A Systematic Review

BACKGROUND AND OBJECTIVE: Cytochromes P450 (CYP) are the major enzymes involved in hepatic metabolism of drugs. Personalization of treatment in pediatrics is a major challenge, as it must not only take into account genetic, environmental, and physiological factors but also ontogeny. Published data i...

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Detalles Bibliográficos
Autores principales: Lenoir, Camille, Rodieux, Frédérique, Desmeules, Jules A., Rollason, Victoria, Samer, Caroline F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613112/
https://www.ncbi.nlm.nih.gov/pubmed/34462878
http://dx.doi.org/10.1007/s40262-021-01064-4