Population Cellular Kinetics of Lisocabtagene Maraleucel, an Autologous CD19-Directed Chimeric Antigen Receptor T-Cell Product, in Patients with Relapsed/Refractory Large B-Cell Lymphoma

BACKGROUND AND OBJECTIVES: Lisocabtagene maraleucel (liso-cel) is a CD19-directed, defined composition, 4-1BB chimeric antigen receptor (CAR) T-cell product administered at equal target doses of CD8(+) and CD4(+) CAR(+) T cells. Large between-subject variability has been noted with CAR T-cell therap...

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Detalles Bibliográficos
Autores principales: Ogasawara, Ken, Dodds, Michael, Mack, Timothy, Lymp, James, Dell’Aringa, Justine, Smith, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613160/
https://www.ncbi.nlm.nih.gov/pubmed/34125421
http://dx.doi.org/10.1007/s40262-021-01039-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613160/
https://www.ncbi.nlm.nih.gov/pubmed/34125421
http://dx.doi.org/10.1007/s40262-021-01039-5

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