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In silico evaluation of the interaction between ACE2 and SARS-CoV-2 Spike protein in a hyperglycemic environment

The worse outcome of COVID-19 in people with diabetes mellitus could be related to the non-enzymatic glycation of human ACE2, leading to a more susceptible interaction with virus Spike protein. We aimed to evaluate, through a computational approach, the interaction between human ACE2 receptor and SA...

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Detalles Bibliográficos
Autores principales: Sartore, Giovanni, Bassani, Davide, Ragazzi, Eugenio, Traldi, Pietro, Lapolla, Annunziata, Moro, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613179/
https://www.ncbi.nlm.nih.gov/pubmed/34819560
http://dx.doi.org/10.1038/s41598-021-02297-w