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In silico evaluation of the interaction between ACE2 and SARS-CoV-2 Spike protein in a hyperglycemic environment
The worse outcome of COVID-19 in people with diabetes mellitus could be related to the non-enzymatic glycation of human ACE2, leading to a more susceptible interaction with virus Spike protein. We aimed to evaluate, through a computational approach, the interaction between human ACE2 receptor and SA...
Autores principales: | Sartore, Giovanni, Bassani, Davide, Ragazzi, Eugenio, Traldi, Pietro, Lapolla, Annunziata, Moro, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613179/ https://www.ncbi.nlm.nih.gov/pubmed/34819560 http://dx.doi.org/10.1038/s41598-021-02297-w |
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