An inducible rodent glaucoma model that exhibits gradual sustained increase in intraocular pressure with distinct inner retina and optic nerve inflammation

Glaucoma is a chronic and progressive neurodegenerative disease of the optic nerve resulting in loss of retinal ganglion cells (RGCs) and vision. The most prominent glaucoma risk factor is increased intraocular pressure (IOP), and most models focus on reproducing this aspect to study disease mechani...

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Detalles Bibliográficos
Autores principales: Mathew, David J., Livne-Bar, Izhar, Sivak, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613281/
https://www.ncbi.nlm.nih.gov/pubmed/34819548
http://dx.doi.org/10.1038/s41598-021-02057-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613281/
https://www.ncbi.nlm.nih.gov/pubmed/34819548
http://dx.doi.org/10.1038/s41598-021-02057-w

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