Nuclear-capture of endosomes depletes nuclear G-actin to promote SRF/MRTF activation and cancer cell invasion

Signals are relayed from receptor tyrosine kinases (RTKs) at the cell surface to effector systems in the cytoplasm and nucleus, and coordination of this process is important for the execution of migratory phenotypes, such as cell scattering and invasion. The endosomal system influences how RTK signa...

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Detalles Bibliográficos
Autores principales: Marco, Sergi, Neilson, Matthew, Moore, Madeleine, Perez-Garcia, Arantxa, Hall, Holly, Mitchell, Louise, Lilla, Sergio, Blanco, Giovani R., Hedley, Ann, Zanivan, Sara, Norman, Jim C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613289/
https://www.ncbi.nlm.nih.gov/pubmed/34819513
http://dx.doi.org/10.1038/s41467-021-26839-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613289/
https://www.ncbi.nlm.nih.gov/pubmed/34819513
http://dx.doi.org/10.1038/s41467-021-26839-y

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