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Trpm5 channels encode bistability of spinal motoneurons and ensure motor control of hindlimbs in mice
Bistable motoneurons of the spinal cord exhibit warmth-activated plateau potential driven by Na(+) and triggered by a brief excitation. The thermoregulating molecular mechanisms of bistability and their role in motor functions remain unknown. Here, we identify thermosensitive Na(+)-permeable Trpm5 c...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613399/ https://www.ncbi.nlm.nih.gov/pubmed/34819493 http://dx.doi.org/10.1038/s41467-021-27113-x |