Conversion from Positive to Negative EGFR Mutation due to Clonal Selection during Long-Term Treatment with Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors: A Case Report

A 77-year-old woman with postoperative recurrent non-small cell lung adenocarcinoma, which exhibited an epidermal growth factor receptor (EGFR) L858R mutation, was treated with gefitinib and erlotinib. Seven years after the start of treatment, the patient experienced a recurrence of malignant pleura...

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Detalles Bibliográficos
Autores principales: Ueda, Masatomo, Namba, Masashi, Tokumo, Kentaro, Senoo, Tadashi, Okamoto, Wataru, Yamauchi, Masami, Hattori, Noboru, Sugiyama, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613632/
https://www.ncbi.nlm.nih.gov/pubmed/34899235
http://dx.doi.org/10.1159/000518246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8613632/
https://www.ncbi.nlm.nih.gov/pubmed/34899235
http://dx.doi.org/10.1159/000518246

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